|
|
L-3-hydroxybutyrate + 2-oxoglutarate <=> (R)-2-hydroxyglutarate + acetoacetate
|
1.1.99.24
hydroxyacid-oxoacid transhydrogenase
|
–
|
|
|
BRENDA:
BR29375
KEGG:
R03225
MetaCyc:
HYDROXYACID-OXOACID-TRANSHYDROGENASE-RXN
SABIO-RK:
3051
|
|
|
|
(R)-2-hydroxyglutarate + acceptor <=> 2-oxoglutarate + reduced_acceptor
|
1.1.99.39
D-2-hydroxyglutarate dehydrogenase
|
–
|
M
|
|
BRENDA:
BR50601
KEGG:
R10575
MetaCyc:
RXN-14932
|
|
|
|
(R)-2-hydroxyglutarate + NAD+ <=> 2-oxoglutarate + NADH + H+
|
1.1.1.399
2-oxoglutarate reductase
1.1.1.95
phosphoglycerate dehydrogenase
1.1.99.2
L-2-hydroxyglutarate dehydrogenase
|
–
–
–
|
BM
|
|
BRENDA:
BR51640
KEGG:
R11337
MetaCyc:
KETOGLUTREDUCT-RXN
SABIO-RK:
15201
|
|
|
|
(R)-2-hydroxyglutarate + pyruvate <=> 2-oxoglutarate + D-lactate
|
1.1.99.40
(R)-2-hydroxyglutarate---pyruvate transhydrogenase
|
–
|
K
|
|
BRENDA:
BR51923
KEGG:
R11593
MetaCyc:
RXN-18432
|
|
|
|
2-oxoglutarate + 4-hydroxybutyrate <=> succinate_semialdehyde + (R)-2-hydroxyglutarate
|
1.1.99.24
hydroxyacid-oxoacid transhydrogenase
|
–
|
|
|
BRENDA:
BS189010
MetaCyc:
RXN-14300
SABIO-RK:
10878
|
|
|
|
acetyl-CoA + (R)-2-hydroxyglutarate <=> acetate + (R)-2-hydroxyglutaryl-1-CoA
|
2.8.3.12
glutaconate CoA-transferase
|
–
|
BM
|
|
BRENDA:
BS360577
MetaCyc:
RXN-1082
|
|
|
|
glutaconyl-CoA + (R)-2-hydroxyglutarate <=> glutaconate + (R)-2-hydroxyglutaryl-1-CoA
|
2.8.3.12
glutaconate CoA-transferase
|
–
|
|
|
BRENDA:
BS360578
SABIO-RK:
13022
|
|
|
|
(R)-2-hydroxyglutarate + oxaloacetate <=> 2-oxoglutarate + D-malate
|
1.1.99.40
(R)-2-hydroxyglutarate---pyruvate transhydrogenase
|
–
|
|
|
MetaCyc:
RXN-18433
|
|
|
|
2-oxoadipate + O2 <=> (R)-2-hydroxyglutarate + CO2
|
1.13.11.M16
|
–
|
M
|
|
MetaCyc:
RXN-21282
|
|
|
|
(R)-2-hydroxyglutarate + 2,6-dichlorophenolindophenol <=> 2-oxoglutarate + reduced_2,6-dichlorophenolindophenol
|
1.1.5.13
(S)-2-hydroxyglutarate dehydrogenase
1.1.99.2
L-2-hydroxyglutarate dehydrogenase
|
–
–
|
|
|
BRENDA:
BS438555
|
|
|
|
2-oxoglutarate + NAD+ <=> (R)-2-hydroxyglutarate + NADH + H+
|
1.1.1.290
4-phosphoerythronate dehydrogenase
|
–
|
|
|
BRENDA:
BS424498
|
|
|
|
beta-hydroxybutyrate + 2-oxoglutarate <=> succinate_semialdehyde + (R)-2-hydroxyglutarate
|
1.1.99.24
hydroxyacid-oxoacid transhydrogenase
|
–
|
|
|
BRENDA:
BS386124
|
|
|
|
(R)-2-hydroxyglutarate + oxaloacetate <=> 2-oxoglutarate + malate
|
1.1.99.40
(R)-2-hydroxyglutarate---pyruvate transhydrogenase
|
–
|
|
|
BRENDA:
BS439373
|
|
|
|
(R)-2-hydroxyglutarate + oxidized_2,6-dichlorophenolindophenol <=> 2-oxoglutarate + reduced_2,6-dichlorophenolindophenol
|
1.1.99.39
D-2-hydroxyglutarate dehydrogenase
|
–
|
|
|
BRENDA:
BS422217
|
|
|
|
H+ + NADPH + 2-oxoglutarate <=> (R)-2-hydroxyglutarate + NADP+
|
1.1.1.42
isocitrate dehydrogenase (NADP+)
|
–
|
|
|
SABIO-RK:
11760
|
|